Search on: MATRIX METALLOPROTEINASE 14 
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Descriptor English:   Matrix Metalloproteinase 14 
Descriptor Spanish:   Metaloproteinasa 14 de la Matriz 
Descriptor Portuguese:   Metaloproteinase 14 da Matriz 
Synonyms English:   MMP 14 Metalloproteinase
MMP X1 Protein
MMP-14 Metalloproteinase
MMP-X1 Protein
MMP14 Metalloproteinase
MT-MMP-1
MT1 Matrix Metalloproteinase
MT1-MMP
MT1-Matrix Metalloproteinase
Membrane Type 1 Matrix Metalloproteinase
Membrane Type Matrix Metalloproteinase 1
Membrane-Type 1 Matrix Metalloproteinase
Membrane-Type Matrix Metalloproteinase 1
Metalloproteinase 14, Matrix
Metalloproteinase, MMP-14
Metalloproteinase, MMP14
Metalloproteinase, MT1-Matrix  
Tree Number:   D08.811.277.656.300.480.525.300.500
D08.811.277.656.675.374.525.300.500
Definition English:   A transmembrane domain-containing matrix metalloproteinase. It is synthesized as an inactive zymogen that is activated by the action of PROPROTEIN CONVERTASES such as FURIN. Matrix metalloproteinase 14 plays a direct role in the cleavage of proteins in the pericellular environment. In addition, it can function indirectly by enzymatically activating the proprotein form of MATRIX METALLOPROTEINASE 15. 
Entry Combination - descr/qualif English:   Matrix Metalloproteinase 14/antagonists & inhibitors use Matrix Metalloproteinase Inhibitors
 
History Note English:   2007(1994) 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Record Number:   52233 
Unique Identifier:   D053511 

Occurrence in VHL:
 

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